BIALLELIC INHERITANCE IN A SINGLE PAKISTANI FAMILY WITH INTELLECTUAL DISABILITY IMPLICATES NEW CANDIDATE GENE RDH14

Biallelic inheritance in a single Pakistani family with intellectual disability implicates new candidate gene RDH14

Abstract In a multi-branch family from Pakistan, individuals presenting with palmoplantar keratoderma segregate in autosomal dominant fashion, and individuals with intellectual disability (ID) segregate in apparent autosomal recessive fashion.Initial attempts to identify the ID locus using homozygosity-by-descent (HBD) mapping were unsuccessful.How

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Terbutaline-triggered fetal arrhythmia prior to neonatal diagnosis of Wolff-Parkinson-White syndrome: A case report

Introduction: Short-term maternal administration of betamimetics is a common obstetric practice with uses including tocolysis during antenatal corticosteroid administration for fetal lung maturity, intrapartum tachysystole, and prior to external cephalic version.While previous research Cup has demonstrated adverse effects of prolonged use of matern

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Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription.

Canine distemper virus (CDV) exhibits a profound lymphotropism that causes immunosuppression and increased susceptibility of affected dogs HR Hand Grip to opportunistic infections.Similar to human measles virus, CDV is supposed to inhibit terminal differentiation of dendritic cells (DCs), responsible for disturbed repopulation of lymphoid tissues a

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